Circulating Monocytes in HIV-1-Infected Viremic Subjects Exhibit an Antiapoptosis Gene Signature and Virus- and Host-Mediated Apoptosis Resistance

Mechanisms that may allow circulating monocytes to persist as CD4 T cells diminish in HIV-1 infection have not been investigated. We have characterized steady-state gene expression signatures in circulating monocytes from HIV-infected subjects and have identified a stable antiapoptosis gene signatur...

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Hlavní autoři: Giri, Malavika S., Nebozyhn, Michael, Raymond, Andrea, Gekonge, Bethsebah, Hancock, Aidan, Creer, Shenoa, Nicols, Calen, Yousef, Malik, Foulkes, Andrea S., Mounzer, Karam, Shull, Jane, Silvestri, Guido, Kostman, Jay, Collman, Ronald G., Showe, Louise, Montaner, Luis J.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2776064/
https://ncbi.nlm.nih.gov/pubmed/19299747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0801450
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