Constitutive Gene Expression in Monocytes from Chronic HIV-1 Infection Overlaps with Acute Toll-Like Receptor Induced Monocyte Activation Profiles

Elevated TLR expression/signalling in monocyte/macrophages has been shown to mediate systemic immune activation, a hallmark of progressive HIV-1 infection. Here we show, via differential gene expression comparisons, the presence of a constitutive in vivo TLR-like gene activation signature in steady-...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Gekonge, Bethsebah, Giri, Malavika S., Kossenkov, Andrew V., Nebozyhn, Michael, Yousef, Malik, Mounzer, Karam, Showe, Louise, Montaner, Luis J.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3399809/
https://ncbi.nlm.nih.gov/pubmed/22815948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0041153
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados