Increased metallothionein gene expression, zinc, and zinc-dependent resistance to apoptosis in circulating monocytes during HIV viremia

Circulating monocytes exhibit an apoptotic resistance phenotype during HIV viremia in association with increased MT expression. MTs are known to play an important role in zinc metabolism and immune function. We now show, in a cross-sectional study using peripheral monocytes, that expression of MT1 i...

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Detalhes bibliográficos
Main Authors: Raymond, Andrea D., Gekonge, Bethsebah, Giri, Malavika S., Hancock, Aidan, Papasavvas, Emmanouil, Chehimi, Jihed, Kossevkov, Andrew V., Nicols, Calen, Yousef, Malik, Mounzer, Karam, Shull, Jane, Kostman, Jay, Showe, Louise, Montaner, Luis J.
Formato: Artigo
Idioma:Inglês
Publicado em: The Society for Leukocyte Biology 2010
Assuntos:
Translational and Clinical Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2924602/
https://ncbi.nlm.nih.gov/pubmed/20551211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.0110051
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