Increased metallothionein gene expression, zinc, and zinc-dependent resistance to apoptosis in circulating monocytes during HIV viremia

Circulating monocytes exhibit an apoptotic resistance phenotype during HIV viremia in association with increased MT expression. MTs are known to play an important role in zinc metabolism and immune function. We now show, in a cross-sectional study using peripheral monocytes, that expression of MT1 i...

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Détails bibliographiques
Auteurs principaux: Raymond, Andrea D., Gekonge, Bethsebah, Giri, Malavika S., Hancock, Aidan, Papasavvas, Emmanouil, Chehimi, Jihed, Kossevkov, Andrew V., Nicols, Calen, Yousef, Malik, Mounzer, Karam, Shull, Jane, Kostman, Jay, Showe, Louise, Montaner, Luis J.
Format: Artigo
Langue:Inglês
Publié: The Society for Leukocyte Biology 2010
Sujets:
Translational and Clinical Immunology
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2924602/
https://ncbi.nlm.nih.gov/pubmed/20551211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.0110051
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