Increased metallothionein gene expression, zinc, and zinc-dependent resistance to apoptosis in circulating monocytes during HIV viremia

Circulating monocytes exhibit an apoptotic resistance phenotype during HIV viremia in association with increased MT expression. MTs are known to play an important role in zinc metabolism and immune function. We now show, in a cross-sectional study using peripheral monocytes, that expression of MT1 i...

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Hauptverfasser: Raymond, Andrea D., Gekonge, Bethsebah, Giri, Malavika S., Hancock, Aidan, Papasavvas, Emmanouil, Chehimi, Jihed, Kossevkov, Andrew V., Nicols, Calen, Yousef, Malik, Mounzer, Karam, Shull, Jane, Kostman, Jay, Showe, Louise, Montaner, Luis J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Society for Leukocyte Biology 2010
Schlagworte:
Translational and Clinical Immunology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2924602/
https://ncbi.nlm.nih.gov/pubmed/20551211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.0110051
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