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Amelioration of the premature ageing-like features of Fgf-23 knockout mice by genetically restoring the systemic actions of FGF-23
Genetic ablation of fibroblast growth factor 23 from mice (Fgf-23(−/−)) results in a short lifespan with numerous abnormal biochemical and morphological features. Such features include kyphosis, hypogonadism and associated infertility, osteopenia, pulmonary emphysema, severe vascular and soft tissue...
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| Huvudupphovsmän: | , , , , , , , , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
2008
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2776048/ https://ncbi.nlm.nih.gov/pubmed/18729070 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/path.2409 |
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