Phosphatidyl Inositol 3-Kinase Signaling in Hypothalamic Proopiomelanocortin Neurons Contributes to the Regulation of Glucose Homeostasis

Recent studies demonstrated a role for hypothalamic insulin and leptin action in the regulation of glucose homeostasis. This regulation involves proopiomelanocortin (POMC) neurons because suppression of phosphatidyl inositol 3-kinase (PI3K) signaling in these neurons blunts the acute effects of insu...

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Main Authors: Hill, Jennifer W., Xu, Yong, Preitner, Frederic, Fukuda, Makota, Cho, You-Ree, Luo, Ji, Balthasar, Nina, Coppari, Roberto, Cantley, Lewis C., Kahn, Barbara B., Zhao, Jean J., Elmquist, Joel K.
Format: Artigo
Language:Inglês
Published: The Endocrine Society 2009
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2775989/
https://ncbi.nlm.nih.gov/pubmed/19819947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2009-0454
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