AURKA F31I Polymorphism and Breast Cancer Risk in BRCA1 and BRCA2 Mutation Carriers: A CIMBA study

The AURKA oncogene is associated with abnormal chromosome segregation and aneuploidy and predisposition to cancer. Amplification of AURKA has been detected at higher frequency in tumors from BRCA1 and BRCA2 mutation carriers than in sporadic breast tumors, suggesting that overexpression of AURKA and...

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Main Authors: Couch, Fergus J., Sinilnikova, Olga, Vierkant, Robert A, Pankratz, V. Shane, Fredericksen, Zachary S., Stoppa-Lyonnet, Dominique, Coupier, Isabelle, Hughes, David, Hardouin, Agnès, Berthet, Pascaline, Peock, Susan, Cook, Margaret, Baynes, Caroline, Hodgson, Shirley, Morrison, Patrick J., Porteous, Mary E., Jakubowska, Anna, Lubinski, Jan, Gronwald, Jacek, Spurdle, Amanda B., Schmutzler, Rita, Versmold, Beatrix, Engel, Christoph, Meindl, Alfons, Sutter, Christian, Horst, Jurgen, Schaefer, Dieter, Offit, Kenneth, Kirchhoff, Tomas, Andrulis, Irene L., Ilyushik, Eduard, Glendon, Gordon, Devilee, Peter, Vreeswijk, Maaike P.G., Vasen, Hans F.A., Borg, Ake, Backenhorn, Katja, Struewing, Jeffery P., Greene, Mark H., Neuhausen, Susan L., Rebbeck, Timothy R., Nathanson, Katherine, Domchek, Susan, Wagner, Theresa, Garber, Judy E., Szabo, Csilla, Zikan, Michal, Foretova, Lenka, Olson, Janet E., Sellers, Thomas A., Lindor, Noralane, Nevanlinna, Heli, Tommiska, Johanna, Aittomaki, Kristiina, Hamann, Ute, Rashid, Muhammad U., Torres, Diana, Simard, Jacques, Durocher, Francine, Guenard, Frederic, Lynch, Henry T., Isaacs, Claudine, Weitzel, Jeffrey, Olopade, Olufunmilayo I., Narod, Steven, Daly, Mary B., Godwin, Andrew K., Tomlinson, Gail, Easton, Douglas F., Chenevix-Trench, Georgia, Antoniouon, Antonis C.
פורמט: Artigo
שפה:Inglês
יצא לאור: 2007
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Article
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2775799/
https://ncbi.nlm.nih.gov/pubmed/17627006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1055-9965.EPI-07-0129
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