AURKA F31I Polymorphism and Breast Cancer Risk in BRCA1 and BRCA2 Mutation Carriers: A CIMBA study

The AURKA oncogene is associated with abnormal chromosome segregation and aneuploidy and predisposition to cancer. Amplification of AURKA has been detected at higher frequency in tumors from BRCA1 and BRCA2 mutation carriers than in sporadic breast tumors, suggesting that overexpression of AURKA and...

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Главные авторы: Couch, Fergus J., Sinilnikova, Olga, Vierkant, Robert A, Pankratz, V. Shane, Fredericksen, Zachary S., Stoppa-Lyonnet, Dominique, Coupier, Isabelle, Hughes, David, Hardouin, Agnès, Berthet, Pascaline, Peock, Susan, Cook, Margaret, Baynes, Caroline, Hodgson, Shirley, Morrison, Patrick J., Porteous, Mary E., Jakubowska, Anna, Lubinski, Jan, Gronwald, Jacek, Spurdle, Amanda B., Schmutzler, Rita, Versmold, Beatrix, Engel, Christoph, Meindl, Alfons, Sutter, Christian, Horst, Jurgen, Schaefer, Dieter, Offit, Kenneth, Kirchhoff, Tomas, Andrulis, Irene L., Ilyushik, Eduard, Glendon, Gordon, Devilee, Peter, Vreeswijk, Maaike P.G., Vasen, Hans F.A., Borg, Ake, Backenhorn, Katja, Struewing, Jeffery P., Greene, Mark H., Neuhausen, Susan L., Rebbeck, Timothy R., Nathanson, Katherine, Domchek, Susan, Wagner, Theresa, Garber, Judy E., Szabo, Csilla, Zikan, Michal, Foretova, Lenka, Olson, Janet E., Sellers, Thomas A., Lindor, Noralane, Nevanlinna, Heli, Tommiska, Johanna, Aittomaki, Kristiina, Hamann, Ute, Rashid, Muhammad U., Torres, Diana, Simard, Jacques, Durocher, Francine, Guenard, Frederic, Lynch, Henry T., Isaacs, Claudine, Weitzel, Jeffrey, Olopade, Olufunmilayo I., Narod, Steven, Daly, Mary B., Godwin, Andrew K., Tomlinson, Gail, Easton, Douglas F., Chenevix-Trench, Georgia, Antoniouon, Antonis C.
Формат: Artigo
Язык:Inglês
Опубликовано: 2007
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2775799/
https://ncbi.nlm.nih.gov/pubmed/17627006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1055-9965.EPI-07-0129
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