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Population genomics in a disease targeted primary cell model

The common genetic variants associated with complex traits typically lie in noncoding DNA and may alter gene regulation in a cell type-specific manner. Consequently, the choice of tissue or cell model in the dissection of disease associations is important. We carried out an expression quantitative t...

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Main Authors: Grundberg, Elin, Kwan, Tony, Ge, Bing, Lam, Kevin C.L., Koka, Vonda, Kindmark, Andreas, Mallmin, Hans, Dias, Joana, Verlaan, Dominique J., Ouimet, Manon, Sinnett, Daniel, Rivadeneira, Fernando, Estrada, Karol, Hofman, Albert, van Meurs, Joyce M., Uitterlinden, André, Beaulieu, Patrick, Graziani, Alexandru, Harmsen, Eef, Ljunggren, Östen, Ohlsson, Claes, Mellström, Dan, Karlsson, Magnus K., Nilsson, Olle, Pastinen, Tomi
格式: Artigo
語言:Inglês
出版: Cold Spring Harbor Laboratory Press 2009
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2775606/
https://ncbi.nlm.nih.gov/pubmed/19654370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.095224.109
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