Population genomics in a disease targeted primary cell model

The common genetic variants associated with complex traits typically lie in noncoding DNA and may alter gene regulation in a cell type-specific manner. Consequently, the choice of tissue or cell model in the dissection of disease associations is important. We carried out an expression quantitative t...

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Autori principali: Grundberg, Elin, Kwan, Tony, Ge, Bing, Lam, Kevin C.L., Koka, Vonda, Kindmark, Andreas, Mallmin, Hans, Dias, Joana, Verlaan, Dominique J., Ouimet, Manon, Sinnett, Daniel, Rivadeneira, Fernando, Estrada, Karol, Hofman, Albert, van Meurs, Joyce M., Uitterlinden, André, Beaulieu, Patrick, Graziani, Alexandru, Harmsen, Eef, Ljunggren, Östen, Ohlsson, Claes, Mellström, Dan, Karlsson, Magnus K., Nilsson, Olle, Pastinen, Tomi
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cold Spring Harbor Laboratory Press 2009
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Letter
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2775606/
https://ncbi.nlm.nih.gov/pubmed/19654370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.095224.109
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