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Distinguishing direct versus indirect transcription factor–DNA interactions

Transcriptional regulation is largely enacted by transcription factors (TFs) binding DNA. Large numbers of TF binding motifs have been revealed by ChIP-chip experiments followed by computational DNA motif discovery. However, the success of motif discovery algorithms has been limited when applied to...

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Detalhes bibliográficos
Main Authors: Gordân, Raluca, Hartemink, Alexander J., Bulyk, Martha L.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2775597/
https://ncbi.nlm.nih.gov/pubmed/19652015
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.094144.109
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