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Common variants on chromosome 6p22.1 are associated with schizophrenia

Schizophrenia, a devastating psychiatric disorder, has a prevalence of 0.5–1%, with high heritability (80–85%) and complex transmission.1 Recent studies implicate rare, large, high-penetrance copy number variants (CNVs) in some cases2, but it is not known what genes or biological mechanisms underlie...

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Bibliografiske detaljer
Main Authors: Shi, Jianxin, Levinson, Douglas F., Duan, Jubao, Sanders, Alan R., Zheng, Yonglan, Pe'er, Itsik, Dudbridge, Frank, Holmans, Peter A., Whittemore, Alice S., Mowry, Bryan J., Olincy, Ann, Amin, Farooq, Cloninger, C. Robert, Silverman, Jeremy M., Buccola, Nancy G., Byerley, William F., Black, Donald W., Crowe, Raymond R., Oksenberg, Jorge R., Mirel, Daniel B., Kendler, Kenneth S., Freedman, Robert, Gejman, Pablo V.
Format: Artigo
Sprog:Inglês
Udgivet: 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2775422/
https://ncbi.nlm.nih.gov/pubmed/19571809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature08192
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