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Overlapping pools for high-throughput targeted resequencing

Resequencing genomic DNA from pools of individuals is an effective strategy to detect new variants in targeted regions and compare them between cases and controls. There are numerous ways to assign individuals to the pools on which they are to be sequenced. The naïve, disjoint pooling scheme (many i...

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Detalhes bibliográficos
Main Authors: Prabhu, Snehit, Pe'er, Itsik
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2704440/
https://ncbi.nlm.nih.gov/pubmed/19447964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.088559.108
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