Genome-Wide Association Study of Clinical Dimensions of Schizophrenia: Polygenic Effect on Disorganized Symptoms

OBJECTIVE: Multiple sources of evidence suggest that genetic factors influence variation in clinical features of schizophrenia. The authors present the first genome-wide association study (GWAS) of dimensional symptom scores among individuals with schizophrenia. METHOD: Based on the Lifetime Dimensi...

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Detalhes bibliográficos
Main Authors: Fanous, Ayman H., Zhou, Baiyu, Aggen, Steven H., Bergen, Sarah E., Amdur, Richard L., Duan, Jubao, Sanders, Alan R., Shi, Jianxin, Mowry, Bryan J., Olincy, Ann, Amin, Farooq, Cloninger, C. Robert, Silverman, Jeremy M., Buccola, Nancy G., Byerley, William F., Black, Donald W., Freedman, Robert, Dudbridge, Frank, Holmans, Peter A., Ripke, Stephan, Gejman, Pablo V., Kendler, Kenneth S., Levinson, Douglas F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3646712/
https://ncbi.nlm.nih.gov/pubmed/23212062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1176/appi.ajp.2012.12020218
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