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Genome-Wide Association Study of Clinical Dimensions of Schizophrenia: Polygenic Effect on Disorganized Symptoms

OBJECTIVE: Multiple sources of evidence suggest that genetic factors influence variation in clinical features of schizophrenia. The authors present the first genome-wide association study (GWAS) of dimensional symptom scores among individuals with schizophrenia. METHOD: Based on the Lifetime Dimensi...

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Main Authors: Fanous, Ayman H., Zhou, Baiyu, Aggen, Steven H., Bergen, Sarah E., Amdur, Richard L., Duan, Jubao, Sanders, Alan R., Shi, Jianxin, Mowry, Bryan J., Olincy, Ann, Amin, Farooq, Cloninger, C. Robert, Silverman, Jeremy M., Buccola, Nancy G., Byerley, William F., Black, Donald W., Freedman, Robert, Dudbridge, Frank, Holmans, Peter A., Ripke, Stephan, Gejman, Pablo V., Kendler, Kenneth S., Levinson, Douglas F.
Formato: Artigo
Idioma:Inglês
Publicado: 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3646712/
https://ncbi.nlm.nih.gov/pubmed/23212062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1176/appi.ajp.2012.12020218
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