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Optimal Experimental Design for Parameter Estimation of a Cell Signaling Model

Differential equation models that describe the dynamic changes of biochemical signaling states are important tools to understand cellular behavior. An essential task in building such representations is to infer the affinities, rate constants, and other parameters of a model from actual measurement d...

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Detalhes bibliográficos
Main Authors: Bandara, Samuel, Schlöder, Johannes P., Eils, Roland, Bock, Hans Georg, Meyer, Tobias
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2775273/
https://ncbi.nlm.nih.gov/pubmed/19911077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1000558
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