Organic Cation Transporters Are Determinants of Oxaliplatin Cytotoxicity

Although the platinum-based anticancer drugs cisplatin, carboplatin, and oxaliplatin have similar DNA-binding properties, only oxaliplatin is active against colorectal tumors. The mechanisms for this tumor specificity of platinum-based compounds are poorly understood but could be related to differen...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
Main Authors: Zhang, Shuzhong, Lovejoy, Katherine S., Shima, James E., Lagpacan, Leah L., Shu, Yan, Lapuk, Anna, Chen, Ying, Komori, Takafumi, Gray, Joe W., Chen, Xin, Lippard, Stephen J., Giacomini, Kathleen M.
Format: Artigo
Jezik:Inglês
Izdano: 2006
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2775093/
https://ncbi.nlm.nih.gov/pubmed/16951202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-06-0769
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki