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Activation of NF-κB by Palmitate in Endothelial Cells: A Key Role for NADPH Oxidase-Derived Superoxide in Response to TLR4 Activation
OBJECTIVE: We investigated whether NADPH oxidase-dependent production of superoxide contributes to activation of NF-κB in endothelial cells by the saturated free fatty acid palmitate. METHODS AND RESULTS: Following incubation of human endothelial cells with palmitate at a concentration known to indu...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2775080/ https://ncbi.nlm.nih.gov/pubmed/19542021 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.109.188813 |
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