CHEMOPREVENTIVE EFFICACY OF NAPROXEN AND NO-NAPROXEN IN RODENT MODELS OF COLON, URINARY BLADDER, AND MAMMARY CANCERS

Nonsteroidal anti-inflammatory drugs (NSAIDs) have been highly effective in preventing colon, urinary bladder, and skin cancer preclinically; and also in clinical trials of colon adenoma formation. However, certain NSAIDs cause gastrointestinal (GI) ulceration and may increase cardiovascular (CV) ev...

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Hlavní autoři: Steele, Vernon E., Rao, Chinthalapally V., Zhang, Yuting, Patlolla, Jagan, Boring, Daniel, Kopelovich, Levy, Juliana, M. Margaret, Grubbs, Clinton J., Lubet, Ronald A.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2774912/
https://ncbi.nlm.nih.gov/pubmed/19892664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1940-6207.CAPR-09-0080
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