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Active site determinants of substrate recognition by the metalloproteinases TACE and ADAM10

The metalloproteinases TACE (ADAM17) and ADAM10 are the primary enzymes responsible for catalyzing release of membrane anchored proteins from the cell surface in metazoan organisms. While the repertoire of protein substrates for these two proteases is partially overlapping, each one appears to targe...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Caescu, Cristina I., Jeschke, Grace R., Turk, Benjamin E.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2009
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2774824/
https://ncbi.nlm.nih.gov/pubmed/19715556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20090549
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