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Active site determinants of substrate recognition by the metalloproteinases TACE and ADAM10
The metalloproteinases TACE (ADAM17) and ADAM10 are the primary enzymes responsible for catalyzing release of membrane anchored proteins from the cell surface in metazoan organisms. While the repertoire of protein substrates for these two proteases is partially overlapping, each one appears to targe...
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| Main Authors: | , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2009
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2774824/ https://ncbi.nlm.nih.gov/pubmed/19715556 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20090549 |
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