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Elucidation of the Proton Transport Mechanism in Human Carbonic Anhydrase II

Human carbonic anhydrase II (HCA II) is one of the fastest known enzymes, which utilizes a rate-limiting proton transport (PT) step in its enzymatic reaction. To evaluate the PT event at an atomistic level, the multistate empirical valence bond (MS-EVB) method has been utilized in this work. It is o...

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書誌詳細
主要な著者: Maupin, C. Mark, McKenna, Robert, Silverman, David N., Voth, Gregory A.
フォーマット: Artigo
言語:Inglês
出版事項: 2009
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2774804/
https://ncbi.nlm.nih.gov/pubmed/19438233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja8091938
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