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Reaction Discovery Employing Macrocycles: Transannular Cyclizations of Macrocyclic Bis-Lactams
[Image: see text] Macrocyclic bis-lactams have been synthesized by cyclodimerization of homoallylic amino esters employing a Zr(IV)-catalyzed ester-amide exchange protocol. Base-mediated transannular cyclizations have been identified to access both bicyclic [5-11] and tricyclic [5-8-5] frameworks in...
שמור ב:
| Main Authors: | , , , , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
2009
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2774802/ https://ncbi.nlm.nih.gov/pubmed/19102683 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol802729f |
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