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Mitochondrial Gene Replacement in Primate Offspring and Embryonic Stem Cells
Mitochondria are found in all eukaryotic cells and contain their own genome (mtDNA). Unlike the nuclear genome which is derived from both the egg and sperm at fertilization, the mtDNA in the embryo are derived almost exclusively from the egg, i.e. is of maternal origin. Mutations in mtDNA contribute...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2009
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2774772/ https://ncbi.nlm.nih.gov/pubmed/19710649 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature08368 |
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