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LAFORIN: A DUAL SPECIFICITY PHOSPHATASE THAT DEPHOSPHORYLATES COMPLEX CARBOHYDRATES

Laforin is the only phosphatase in the animal kingdom that contains a carbohydrate-binding module (CBM). Mutations in the gene encoding laforin result in Lafora disease (LD), a fatal autosomal recessive neurodegenerative disorder, which is diagnosed by the presence of intracellular deposits of insol...

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Autori principali: Worby, Carolyn A., Gentry, Matthew S., Dixon, Jack E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2006
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2774450/
https://ncbi.nlm.nih.gov/pubmed/16901901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M606117200
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