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Motif-directed flexible backbone design of functional interactions
Computational protein design relies on a number of approximations to efficiently search the huge sequence space available to proteins. The fixed backbone and rotamer approximations in particular are important for formulating protein design as a discrete combinatorial optimization problem. However, t...
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| Autori principali: | , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Wiley Subscription Services, Inc., A Wiley Company
2009
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2774439/ https://ncbi.nlm.nih.gov/pubmed/19472357 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.142 |
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