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Racemic crystallography of synthetic protein enantiomers used to determine the X-ray structure of plectasin by direct methods
We describe the use of racemic crystallography to determine the X-ray structure of the natural product plectasin, a potent antimicrobial protein recently isolated from fungus. The protein enantiomers l-plectasin and d-plectasin were prepared by total chemical synthesis; interestingly, l-plectasin sh...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Wiley Subscription Services, Inc., A Wiley Company
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2774425/ https://ncbi.nlm.nih.gov/pubmed/19472324 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.127 |
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