Virus neutralization by germ-line vs. hypermutated antibodies
Mice infected with vesicular stomatitis virus (VSV), a cytopathic virus closely related to rabies virus, mount a virus-neutralizing antibody response protecting against lethal disease. VSVneutralizing monoclonal IgGs isolated from primary immune responses were devoid of somatic mutations, whereas mo...
Salvato in:
| Pubblicato in: | Proc Natl Acad Sci U S A |
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| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
2000
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC27744/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10963674/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.97.18.10126 |
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