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Optical Detection of Disordered Water Within a Protein Cavity
Internal water molecules are important to protein structure and function, but positional disorder and low occupancies can obscure their detection by x-ray crystallography. Here we show that water can be detected within the distal cavities of myoglobin mutants by subtle changes in the absorbance spec...
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| Autori principali: | , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2009
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2774273/ https://ncbi.nlm.nih.gov/pubmed/19655795 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja903409j |
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