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Co-evolution of KIR2DL3 with HLA-C in a human population retaining minimal essential diversity of KIR and HLA class I ligands

Natural killer (NK) cells contribute to immunity and reproduction. Guiding these functions, and NK cell education, are killer cell Ig-like receptors (KIR), NK cell receptors that recognize HLA class I. In most human populations, these highly polymorphic receptors and ligands combine with extraordina...

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Библиографические подробности
Главные авторы: Gendzekhadze, Ketevan, Norman, Paul J., Abi-Rached, Laurent, Graef, Thorsten, Moesta, Achim K., Layrisse, Zulay, Parham, Peter
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 2009
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2774017/
https://ncbi.nlm.nih.gov/pubmed/19837691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0906051106
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