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In ovo application of antagomiRs indicates a role for miR-196 in patterning the chick axial skeleton through Hox gene regulation

Patterning of the vertebrate axial skeleton requires precise spatial and temporal control of Hox gene expression during embryonic development. MicroRNAs (miRNAs) are recently described modulators of gene activity, and members of the miR-196 and miR-10 families have been shown to target several Hox g...

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Autors principals: McGlinn, Edwina, Yekta, Soraya, Mansfield, Jennifer H., Soutschek, Jürgen, Bartel, David P., Tabin, Clifford J.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2009
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2773993/
https://ncbi.nlm.nih.gov/pubmed/19846767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0910374106
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