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In ovo application of antagomiRs indicates a role for miR-196 in patterning the chick axial skeleton through Hox gene regulation

Patterning of the vertebrate axial skeleton requires precise spatial and temporal control of Hox gene expression during embryonic development. MicroRNAs (miRNAs) are recently described modulators of gene activity, and members of the miR-196 and miR-10 families have been shown to target several Hox g...

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Autori principali: McGlinn, Edwina, Yekta, Soraya, Mansfield, Jennifer H., Soutschek, Jürgen, Bartel, David P., Tabin, Clifford J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2773993/
https://ncbi.nlm.nih.gov/pubmed/19846767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0910374106
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