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Potential therapeutic role of antagomiR17 for the treatment of chronic lymphocytic leukemia
Recently it was reported that microRNA from the miR-17 ~ 92 family may have a key role in chronic lymphocytic leukemia (CLL). Here, we designed specific oligonucleotides to target endogenous miR-17 (antagomiR17). In-vitro administration of antagomiR17 effectively reduced miR-17 expression and the pr...
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| Auteurs principaux: | , , , , , , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
BioMed Central
2014
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4210490/ https://ncbi.nlm.nih.gov/pubmed/25339346 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13045-014-0079-z |
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