Potential therapeutic role of antagomiR17 for the treatment of chronic lymphocytic leukemia

Recently it was reported that microRNA from the miR-17 ~ 92 family may have a key role in chronic lymphocytic leukemia (CLL). Here, we designed specific oligonucleotides to target endogenous miR-17 (antagomiR17). In-vitro administration of antagomiR17 effectively reduced miR-17 expression and the pr...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Dereani, Sara, Macor, Paolo, D’Agaro, Tiziana, Mezzaroba, Nelly, Dal-Bo, Michele, Capolla, Sara, Zucchetto, Antonella, Tissino, Erika, Del Poeta, Giovanni, Zorzet, Sonia, Gattei, Valter, Bomben, Riccardo
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2014
Sujets:
Letter to the Editor
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4210490/
https://ncbi.nlm.nih.gov/pubmed/25339346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13045-014-0079-z
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