Mapping of multiple susceptibility variants within the MHC region for 7 immune-mediated diseases

The human MHC represents the strongest susceptibility locus for autoimmune diseases. However, the identification of the true predisposing gene(s) has been handicapped by the strong linkage disequilibrium across the region. Furthermore, most studies to date have been limited to the examination of a s...

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Bibliographic Details
Main Authors: Rioux, John D., Goyette, Philippe, Vyse, Timothy J., Hammarström, Lennart, Fernando, Michelle M. A., Green, Todd, De Jager, Philip L., Foisy, Sylvain, Wang, Joanne, de Bakker, Paul I. W., Leslie, Stephen, McVean, Gilean, Padyukov, Leonid, Alfredsson, Lars, Annese, Vito, Hafler, David A., Pan-Hammarström, Qiang, Matell, Ritva, Sawcer, Stephen J., Compston, Alastair D., Cree, Bruce A. C., Mirel, Daniel B., Daly, Mark J., Behrens, Tim W., Klareskog, Lars, Gregersen, Peter K., Oksenberg, Jorge R., Hauser, Stephen L.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2009
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2773992/
https://ncbi.nlm.nih.gov/pubmed/19846760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0909307106
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