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NON-COMPETITIVE PEAK DECAY ANALYSIS OF DRUG-PROTEIN DISSOCIATION BY HIGH-PERFORMANCE AFFINITY CHROMATOGRAPHY

The peak decay method is an affinity chromatographic technique that has been used to examine the dissociation of solutes from immobilized ligands in the presence of excess displacing agent. However, it can be difficult to find a displacing agent that does not interfere with detection of the eluting...

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Detalhes bibliográficos
Main Authors: Chen, Jianzhong, Schiel, John E., Hage, David S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2773687/
https://ncbi.nlm.nih.gov/pubmed/19472288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jssc.200900074
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