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Effects of 4-Aminopyridine on Cloned hERG Channels Expressed in Mammalian Cells
INTRODUCTION: Non-clinical evaluation of a medication's potential to induce cardiac toxicity is recommended by regulatory agencies. 4-Aminopyridine (fampridine) is a potassium channel blocker with the demonstrated ability to improve walking ability in patients with multiple sclerosis. We evalua...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Blackwell Publishing Inc
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2773527/ https://ncbi.nlm.nih.gov/pubmed/19915712 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1753-5174.2009.00021.x |
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