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Filter-based hybridization capture of subgenomes enables resequencing and copy-number detection
To exploit contemporary sequencing technologies for targeted genetic analyses, we developed a hybridization enrichment strategy for DNA capture that uses PCR products as subgenomic traps. We applied this strategy to 115 kb of the human genome encompassing 47 genes implicated in cardiovascular diseas...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2773433/ https://ncbi.nlm.nih.gov/pubmed/19543287 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth.1343 |
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