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Disruption of Mitochondrial DNA Replication in Drosophila Increases Mitochondrial Fast Axonal Transport In Vivo

Mutations in mitochondrial DNA polymerase (pol γ) cause several progressive human diseases including Parkinson's disease, Alper's syndrome, and progressive external ophthalmoplegia. At the cellular level, disruption of pol γ leads to depletion of mtDNA, disrupts the mitochondrial respirato...

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Autori principali: Baqri, Rehan M., Turner, Brittany A., Rheuben, Mary B., Hammond, Bradley D., Kaguni, Laurie S., Miller, Kyle E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2773408/
https://ncbi.nlm.nih.gov/pubmed/19924234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0007874
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