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Mitochondrial Chaperone TRAP1 Activates the Mitochondrial UPR and Extends Healthspan in Drosophila
The molecular mechanisms influencing healthspan are unclear but mitochondrial function, resistance to oxidative stress and proteostasis are recurring themes. Tumor necrosis factor Receptor Associated Protein 1 (TRAP1), the mitochondrial analogue of Hsp75, regulates levels of reactive oxygen species...
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| Publicado no: | Mech Ageing Dev |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4310785/ https://ncbi.nlm.nih.gov/pubmed/25265088 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mad.2014.09.002 |
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