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Importance of Charge Independent Effects in Readout of the Trimethyllysine Mark by HP1 Chromodomain

Histone modifications are implicated in epigenetic inheritance, and are of central importance in regulating chromatin structure and gene expression. A prototype example is the tri-methylation (Me3) of lysine 9 on histone 3 (H3), which is readout by an aromatic cage of the chromodomain of heterochrom...

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Bibliographic Details
Main Authors: Lu, Zhenyu, Lai, Jonathan, Zhang, Yingkai
Format: Artigo
Language:Inglês
Published: 2009
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2773244/
https://ncbi.nlm.nih.gov/pubmed/19788305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja904951t
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