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FcRn-mediated antibody transport across epithelial cells revealed by electron tomography

The neonatal Fc receptor (FcRn) transports maternal IgG across epithelial barriers1,2, thereby providing the fetus or newborn with humoral immunity before its immune system is fully functional. In newborn rodents, FcRn transfers IgG from milk to blood by apical-to-basolateral transcytosis across int...

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Détails bibliographiques
Auteurs principaux: He, Wanzhong, Ladinsky, Mark S., Huey-Tubman, Kathryn E., Jensen, Grant J., McIntosh, J. Richard, Björkman, Pamela J.
Format: Artigo
Langue:Inglês
Publié: 2008
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2773227/
https://ncbi.nlm.nih.gov/pubmed/18818657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature07255
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