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FcRn-mediated antibody transport across epithelial cells revealed by electron tomography

The neonatal Fc receptor (FcRn) transports maternal IgG across epithelial barriers1,2, thereby providing the fetus or newborn with humoral immunity before its immune system is fully functional. In newborn rodents, FcRn transfers IgG from milk to blood by apical-to-basolateral transcytosis across int...

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Detalhes bibliográficos
Main Authors: He, Wanzhong, Ladinsky, Mark S., Huey-Tubman, Kathryn E., Jensen, Grant J., McIntosh, J. Richard, Björkman, Pamela J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2773227/
https://ncbi.nlm.nih.gov/pubmed/18818657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature07255
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