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In Translation: FcRn across the Therapeutic Spectrum
As an essential modulator of IgG disposition, the neonatal Fc receptor (FcRn) governs the pharmacokinetics and functions many therapeutic modalities. In this review, we thoroughly reexamine the hitherto elucidated biological and thermodynamic properties of FcRn to provide context for our assessment...
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| 發表在: | Int J Mol Sci |
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| Main Authors: | , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
MDPI
2021
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8002405/ https://ncbi.nlm.nih.gov/pubmed/33802650 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22063048 |
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