Development and Preclinical Testing of a High Affinity Single Chain Antibody against (+)-Methamphetamine

Chronic or excessive (+)-methamphetamine (METH) use often leads to addiction and toxicity to critical organs like the brain. With medical treatment as a goal, a novel single chain variable fragment (scFv) against METH was engineered from anti-METH monoclonal antibody mAb6H4 (IgG, κ light chain, K(D)...

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Bibliografiske detaljer
Main Authors: Peterson, Eric C., Laurenzana, Elizabeth M., Atchley, William T., Hendrickson, Howard, Owens, S. Michael
Format: Artigo
Sprog:Inglês
Udgivet: 2008
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2773181/
https://ncbi.nlm.nih.gov/pubmed/18192498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.107.134395
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