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Development and Preclinical Testing of a High Affinity Single Chain Antibody against (+)-Methamphetamine
Chronic or excessive (+)-methamphetamine (METH) use often leads to addiction and toxicity to critical organs like the brain. With medical treatment as a goal, a novel single chain variable fragment (scFv) against METH was engineered from anti-METH monoclonal antibody mAb6H4 (IgG, κ light chain, K(D)...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2008
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2773181/ https://ncbi.nlm.nih.gov/pubmed/18192498 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.107.134395 |
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