A Genome-wide siRNA Screen Reveals Diverse Cellular Processes and Pathways that Mediate Genome Stability

Signaling pathways that respond to DNA damage are essential for the maintenance of genome stability and are linked to many diseases, including cancer. Here, a genome-wide siRNA screen was employed to identify novel genes involved in genome stabilization by monitoring phosphorylation of the histone v...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Paulsen, Renee D., Soni, Deena V., Wollman, Roy, Hahn, Angela T., Yee, Muh-Ching, Guan, Anna, Hesley, Jayne A., Miller, Steven C., Cromwell, Evan F., Solow-Cordero, David E., Meyer, Tobias, Cimprich, Karlene A.
التنسيق: Artigo
اللغة:Inglês
منشور في: 2009
الموضوعات:
Article
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC2772893/
https://ncbi.nlm.nih.gov/pubmed/19647519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2009.06.021
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