A Genome-wide siRNA Screen Reveals Diverse Cellular Processes and Pathways that Mediate Genome Stability

Signaling pathways that respond to DNA damage are essential for the maintenance of genome stability and are linked to many diseases, including cancer. Here, a genome-wide siRNA screen was employed to identify novel genes involved in genome stabilization by monitoring phosphorylation of the histone v...

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Autores principales: Paulsen, Renee D., Soni, Deena V., Wollman, Roy, Hahn, Angela T., Yee, Muh-Ching, Guan, Anna, Hesley, Jayne A., Miller, Steven C., Cromwell, Evan F., Solow-Cordero, David E., Meyer, Tobias, Cimprich, Karlene A.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2009
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2772893/
https://ncbi.nlm.nih.gov/pubmed/19647519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2009.06.021
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