A Genome-wide siRNA Screen Reveals Diverse Cellular Processes and Pathways that Mediate Genome Stability

Signaling pathways that respond to DNA damage are essential for the maintenance of genome stability and are linked to many diseases, including cancer. Here, a genome-wide siRNA screen was employed to identify novel genes involved in genome stabilization by monitoring phosphorylation of the histone v...

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書誌詳細
主要な著者: Paulsen, Renee D., Soni, Deena V., Wollman, Roy, Hahn, Angela T., Yee, Muh-Ching, Guan, Anna, Hesley, Jayne A., Miller, Steven C., Cromwell, Evan F., Solow-Cordero, David E., Meyer, Tobias, Cimprich, Karlene A.
フォーマット: Artigo
言語:Inglês
出版事項: 2009
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2772893/
https://ncbi.nlm.nih.gov/pubmed/19647519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2009.06.021
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