A Genome-wide siRNA Screen Reveals Diverse Cellular Processes and Pathways that Mediate Genome Stability

Signaling pathways that respond to DNA damage are essential for the maintenance of genome stability and are linked to many diseases, including cancer. Here, a genome-wide siRNA screen was employed to identify novel genes involved in genome stabilization by monitoring phosphorylation of the histone v...

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Bibliographic Details
Main Authors: Paulsen, Renee D., Soni, Deena V., Wollman, Roy, Hahn, Angela T., Yee, Muh-Ching, Guan, Anna, Hesley, Jayne A., Miller, Steven C., Cromwell, Evan F., Solow-Cordero, David E., Meyer, Tobias, Cimprich, Karlene A.
Format: Artigo
Language:Inglês
Published: 2009
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2772893/
https://ncbi.nlm.nih.gov/pubmed/19647519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2009.06.021
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