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Antifibrotic Effects of Antioxidant N-Acetylcysteine in a Mouse Model of Human Hypertrophic Cardiomyopathy Mutation

OBJECTIVES: The objective was to determine the effects of antioxidant N-acetylcysteine (NAC) on reversal and attenuation of established interstitial fibrosis in the cardiac troponin T (cTnT) mouse model of human hypertrophic cardiomyopathy (HCM) mutation. BACKGROUND: Interstitial fibrosis is a chara...

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Main Authors: Marian, Ali J., Senthil, Vinitha, Chen, Suet N., Lombardi, Raffaella
Format: Artigo
Jezik:Inglês
Izdano: 2006
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2772865/
https://ncbi.nlm.nih.gov/pubmed/16487852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jacc.2005.10.041
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