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Role of L2 cysteines in papillomavirus infection and neutralization

Vaccination of mice with minor capsid protein L2 or passive transfer with the L2-specific neutralizing monoclonal antibody RG-1 protects against human papillomavirus type 16 (HPV16) challenge. Here we explored the nature of the RG-1 epitope and its contribution to viral infectivity. RG-1 bound equiv...

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Detalhes bibliográficos
Main Authors: Gambhira, Ratish, Jagu, Subhashini, Karanam, Balasubramanyam, Day, Patricia M, Roden, Richard
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2772844/
https://ncbi.nlm.nih.gov/pubmed/19860897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1743-422X-6-176
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