A Protective and Broadly Cross-Neutralizing Epitope of Human Papillomavirus L2

We generated a monoclonal antibody, RG-1, that binds to highly conserved L2 residues 17 to 36 and neutralizes human papillomavirus 16 (HPV16) and HPV18. Passive immunotherapy with RG-1 was protective in mice. Antiserum to the HPV16 L2 peptide comprising residues 17 to 36 (peptide 17-36) neutralized...

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Detalhes bibliográficos
Main Authors: Gambhira, Ratish, Karanam, Balasubramanyam, Jagu, Subhashini, Roberts, Jeffrey N., Buck, Christopher B., Bossis, Ioannis, Alphs, Hannah, Culp, Timothy, Christensen, Neil D., Roden, Richard B. S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2007
Assuntos:
Vaccines and Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2168823/
https://ncbi.nlm.nih.gov/pubmed/17928339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00936-07
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