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Protection against heterologous human papillomavirus challenge by a synthetic lipopeptide vaccine containing a broadly cross-neutralizing epitope of L2

Persistent infection with the high-risk subset of genitotropic human papillomavirus (HPV) genotypes is a necessary cause of cervical cancer. Given the global burden of cervical cancer, a low-cost, broadly protective vaccine is needed. RG-1 is a cross-neutralizing and protective monoclonal antibody t...

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Hlavní autoři: Alphs, Hannah H., Gambhira, Ratish, Karanam, Balasubramanyam, Roberts, Jeffrey N., Jagu, Subhashini, Schiller, John T., Zeng, Weiguang, Jackson, David C., Roden, Richard B. S.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2299222/
https://ncbi.nlm.nih.gov/pubmed/18413606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0800868105
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